| 发明名称 |
IMMUNOPOTENTIATING INOSINE MONOPHOSPHATE 5'-NUCLEOTIDASE RESISTANT DERIVATIVES AND USES THEREOF |
| 摘要 |
<p>A method of making inosine-5'-monophosphate and its derivatives resistant to 5'-nucleotidase by chemically modifying inosine-5'-monophosphate to formula (I) wherein R is selected from the group consisting of an alkyl, alkoxy and secondary amino compounds whereby inosine-5'-monophosphate biological activity is retained in vivo.</p> |
| 申请公布号 |
CA2675757(A1) |
申请公布日期 |
1996.10.24 |
| 申请号 |
CA19952675757 |
申请日期 |
1995.04.21 |
| 申请人 |
UNIVERSITY OF SOUTH FLORIDA |
发明人 |
MASIHI, K. NOEL;GINER-SOROLLA, ALFREDO;HADDEN, JOHN W. |
| 分类号 |
A61K39/39;C07H19/20;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7076;A61K31/708;A61K39/29;A61P31/00;A61P31/04;A61P31/12;A61P35/00;A61P37/02;A61P37/04;C07H19/10 |
主分类号 |
A61K39/39 |
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