| 摘要 |
Neuropeptides, particularly vasoactive intestinal peptide (VIP) and fragment s, mutations and derivatives thereof that have corresponding activities to whic h have been directly or indirectly linked at least one NO or NO2 group, and their uses, including the relaxation of smooth muscle in several tissues, including vascular smooth muscle (e.g., aorta) and nonvascular smooth muscle (e.g. trachea, sphincter of Oddi, gastrointestinal smooth muscle and corpus cavernosum smooth muscle), and particularly also for the diagnosis and treatment of human male impotence.
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