发明名称 |
PREPARATION OF CLAVULANATE SALTS |
摘要 |
A process for preparation and/or purification of clavulanic acid or a pharmaceutically acceptable salt or ester thereof, including the steps of: adding an additional solvent to a solution of clavulanic acid in a water immiscible solvent; contacting the solution with an amine; isolating the amine salt of clavulanic acid formed; and converting the amine salt into clavulanic acid or a pharmaceutically acceptable salt or ester thereof.
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申请公布号 |
CA2218648(A1) |
申请公布日期 |
1996.10.24 |
申请号 |
CA19962218648 |
申请日期 |
1996.04.17 |
申请人 |
LEK PHARMACEUTICAL & CHEMICAL CO.DD |
发明人 |
CAPUDER, EGIDIJ |
分类号 |
A61K31/42;A61P31/04;C07D503/00;C07D503/08;C07D503/18;(IPC1-7):C07D503/02;C12P17/18 |
主分类号 |
A61K31/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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