摘要 |
Provided are pharmaceutical formulations, and methods of inhibiting fungal and parasitic activity using a compound of formula I: <CHEM> wherein: R' is hydrogen, methyl or NH2C(O)CH2-; R'' and R''' are independently methyl or hydrogen; R<x1>, R<x2>, R<y1>, R<y2>, R<y3>, and R<y4> are independently hydroxy or hydrogen; R0 is a group of the formula <CHEM> R1 is C1-C6 alkyl, C1-C6 alkoxy, phenyl, p-halo-phenyl, p-nitrophenyl, phenoxy, benzyl, p-halo-benzyl, or p-nitro-benzyl; and R2 is an acyl side chain as defined herein. |