| 摘要 |
PCT No. PCT/US91/09294 Sec. 371 Date Apr. 22, 1993 Sec. 102(e) Date Apr. 22, 1993 PCT Filed Dec. 6, 1991 PCT Pub. No. WO92/10589 PCT Pub. Date Jun. 25, 1992Primers for amplification of specific nucleic acid sequences of the second exon of HLA DRbeta genes and probes for identifying polymorphic sequences contained in the amplified DNA can be used in processes for typing homozygous or heterozygous samples from a variety of sources and for detecting allelic variants not distinguishable by serological methods. This HLA DRbeta DNA typing system can be used in a dot-blot format that is simple and rapid to perform, produces detectable signals in minutes, and can be used for tissue typing, determining individual identity, and identifying disease susceptible individuals.
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