发明名称 IMIDAZOPYRIDINE DERIVATIVES, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF ITS PREPARING
摘要 FIELD: organic chemistry. SUBSTANCE: product: new derivatives of imidazopyridine of the formula (I)where R meansand R,R,R,R,Ar, X and Y have values indicated in point 1 of invention. Salts of proposed compounds show antagonistic properties with respect to angiotensin-II and can be used for treatment of hypertension, aldosteronism, cardiac failure, increased intraocular pressure and central nervous system disorders. EFFECT: improved method of synthesis, enhanced effectiveness of compounds proposed.
申请公布号 RU94042907(A) 申请公布日期 1996.10.20
申请号 RU19940042907 申请日期 1994.12.05
申请人 MERK PATENT GMBKH 发明人 VERNER MEDERSKI;DITER DORSH;MATIAS OSVAL'D;NORBERT BAJER;P'ER SHELLING;KLAUS-OTTO MINK;INGEBORG LU
分类号 A61K31/435;A61K31/445;A61K31/47;A61K31/495;A61P9/00;A61P9/12;A61P27/02;A61P43/00;C07D471/04 主分类号 A61K31/435
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