| 发明名称 |
NOVEL SUBSTITUTED PIPERAZINE DERIVATIVES HAVING TACHYKININ RECEPTOR ANTAGONISTS ACTIVITY |
| 摘要 |
The present invention relates to substituted piperazine derivatives (herein referred to as compounds or compounds of formula (1), or stereoisomers, or pharmaceutically acceptable salts thereof and their use as tachykinin receptor antagonists. Such antagonists are useful in the treatment of tachykininmediated diseases and conditions disclosed herein including: asthma, cough, and bronchitis.
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| 申请公布号 |
CA2217006(A1) |
申请公布日期 |
1996.10.17 |
| 申请号 |
CA19962217006 |
申请日期 |
1996.03.11 |
| 申请人 |
HOECHST MARION ROUSSEL, INC.;MARION MERRELL DOW INC. |
发明人 |
LE, TIEU-BINH;KUDLACZ, ELIZABETH M.;BURKHOLDER, TIMOTHY P. |
| 分类号 |
C07D241/04;A61K31/50;A61P1/00;A61P1/08;A61P11/00;A61P25/00;A61P25/02;A61P25/04;A61P25/18;A61P25/20;A61P25/24;A61P25/26;A61P25/28;A61P27/02;A61P27/14;A61P29/00;A61P37/00;A61P37/08;A61P43/00;C07D241/08;C07D309/12;C07D403/06;(IPC1-7):C07D241/08;C07D403/00;A61K31/495 |
主分类号 |
C07D241/04 |
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