摘要 |
Pharmaceutical compositions comprising as active ingredient a synthetic random copolymer of average molecular weight of about 4,000-12,000, preferably 6,000-8,000, said copolymer consisting of glutamic acid (Glu), lysine (Lys), alanine (Ala) and tyrosine (Tyr) residues in a relative molar ratio of 1.4-2.1 parts of Glu to 3.2-5.0 parts of Lys to 4.0-6.6 parts of Ala to 1.0 parts of Tyr (herein GLAT copolymers), can be used in a method for prevention and treatment of graft-versus-host disease in patients in the course of bone marrow and organ transplantation.
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申请人 |
YEDA RESEARCH AND DEVELOPMENT CO. LTD.;BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UN;AHARONI, RINA;ARNON, RUTH;CHAO, NELSON, J.;SCHLEGEL, PAUL, G.;SELA, MICHAEL;TEITELBAUM, DVORA |
发明人 |
AHARONI, RINA;ARNON, RUTH;CHAO, NELSON, J.;SCHLEGEL, PAUL, G.;SELA, MICHAEL;TEITELBAUM, DVORA |