| 发明名称 |
POLYSACCHARIDE-BOUND NITRIC OXIDE-NUCLEOPHILE ADDUCTS |
| 摘要 |
A polymeric composition capable of releasing nitric oxide comprises a polysaccharide including a nitric oxide-releasing N2O2- functional group bound to the polymer; pharmaceutical compositions including the polymeric composition; and methods for treating biological disorders in which dosage with nitric oxide is beneficial. The compositions can be used as and/or incorporated into implants, injectables, condoms, prosthesis coatings, patches, and the like for use in a wide variety of medical applications.
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| 申请公布号 |
CA2216696(A1) |
申请公布日期 |
1996.10.17 |
| 申请号 |
CA19962216696 |
申请日期 |
1996.04.10 |
| 申请人 |
UNIVERSITY OF AKRON;THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT O F HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH |
发明人 |
CHAKRAVARTHY, DEBASHISH;KEEFER, LARRY K.;SMITH, DANIEL J. |
| 分类号 |
A61K31/655;A61K31/785;A61K47/48;C08F8/30;(IPC1-7):A61K33/00;A61K31/735 |
主分类号 |
A61K31/655 |
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