发明名称 Drug containing methotrexate derivative
摘要 Compounds represented by general formula (I) or salts thereof, (wherein R1 represents a member selected from the group consisting of CH2, CH2CH2, CH2O, CH2S and CH2SO; R2 represents hydrogen, lower (C1-4) alkyl or benzyl; R3 represents COOR4, NHCOR5, CONR6R7, PO3H2 or SO3H; and n is an integer of from 1 to 4) which are useful as a remedy for autoimmune diseases such as systemic lupus erythematosus or nephritis such as glomerulonephritis. <CHEM> <IMAGE>
申请公布号 AU5015896(A) 申请公布日期 1996.10.16
申请号 AU19960050158 申请日期 1996.03.26
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人 MASAHIKO MIHARA
分类号 A61K31/519;A61K31/5415;C07D475/08 主分类号 A61K31/519
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