Anti-stroke effects of calcium antagonists

摘要

The present invention provides a method of treating a cerebrovascular disease in an animal comprising the step of administering to an animal in need of such treatment a therapeutically effective dose of a calcium channel antagonist. Also provided is a method of inhibiting the proliferation of vascular smooth muscle cells in an animal comprising the step of administering to an animal in need of such treatment a pharmacologically effective dose of a calcium channel antagonist. Further provided is a method of inhibiting the expression of transcription factor AP-1 in an animal comprising the step of administering to an animal in need of such treatment a pharmacologically effective dose of a calcium channel antagonist.