发明名称 Smooth muscle cell proliferation inhibitors
摘要 This invention comprises polyanionic benzylglycosides of benzene triacid amides of the general formula I <IMAGE> I wherein each of R1, R2, R3, and R4 are, independently, H, SO3M, or <IMAGE> and each oligosaccharide group contains 1 to 3 sugar groups; M is lithium, sodium, potassium, or ammonium; n is 1 or 2; X is a halogen, lower alkyl having 1 to 6 carbon atoms, or lower alkoxy having 1 to 6 carbon atoms; Y is carbonyl or sulfonyl; or the pharmaceutically acceptable salts thereof, as well as their use as smooth muscle cell antiproliferation inhibitors and as therapeutic compositions for treating diseases and conditions which are characterized by excessive smooth muscle proliferation.
申请公布号 US5565432(A) 申请公布日期 1996.10.15
申请号 US19940335010 申请日期 1994.11.07
申请人 AMERICAN HOME PRODUCTS CORPORATION 发明人 NOVAK, SARAH T.A.;SOLL, RICHARD M.
分类号 C07H15/18;A61K31/70;A61K31/7028;A61P9/00;A61P43/00;C07H15/203;(IPC1-7):A61K31/70;A61K31/705;C07H15/00 主分类号 C07H15/18
代理机构 代理人
主权项
地址