2,4,5-trihalogeno-and 2,3,4,5-tetrahalogenobenzene derivatives

摘要

2,4,5-Trihalogenobenzene derivatives of the formula <IMAGE> is which R is -COOH, -COCl, -COF, -CN, -CONH2, -CH2OH, -CH2Cl, -CHCl2, -CCl3 or -CHO, R1 is H, Cl or F, and R2 is Cl or F, it only being possible for R1 or R2 to be F, and processes for their preparation starting from benzonitriles reacted with potassium fluoride. The novel compounds are intermediates for antibacterials such as quinolone carboxylic acids.