发明名称 |
Hybridoma-producing NSO myeloma cell line |
摘要 |
This invention relates to an NSO myeloma cell line which has increased fusion frequency, and to a method of producing said cell line. The NSO cell line of the invention, when fused with B cells, produces monoclonal antibody-secreting hybridoma which has increased resistance to death. In addition, the monoclonal antibodies secreted by said hybridomas have increased affinity for foreign antigens and for autoantigens.
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申请公布号 |
US5565337(A) |
申请公布日期 |
1996.10.15 |
申请号 |
US19940294416 |
申请日期 |
1994.08.23 |
申请人 |
ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY, A DIVISION OF YESHIVA UNIVERSITY |
发明人 |
DIAMOND, BETTY A.;RAY, SUBHRANSU |
分类号 |
C12N5/16;C12P21/08;(IPC1-7):C12P21/08;C07K16/00;C12N5/12;C12N15/02 |
主分类号 |
C12N5/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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