发明名称 |
Hepatitis A virus in a reconstituted influenza virosome and use as a vaccine |
摘要 |
Disclosed are immunostimulating reconstituted influenza virosomes (IRIVs) comprising reconstituted functional virus envelopes containing an inactivated hepatitis A virus and an influenza hemagglutinin protein (HA) or a peptide with the amino terminal 21 amino acid residue segment of HA2 which induces the fusion of the IRIVs with cellular membranes and the lysis of the IRIV. A vaccine containing the hepatitis A IRIVs is also disclosed.
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申请公布号 |
US5565203(A) |
申请公布日期 |
1996.10.15 |
申请号 |
US19930965246 |
申请日期 |
1993.03.03 |
申请人 |
SCHWEIZ. SERUM- & IMPFINSTITUT BERN |
发明人 |
GL+E,UML U+EE CK, REINHARD;MISCHLER, ROBERT |
分类号 |
A61K39/002;A61K9/127;A61K9/133;A61K39/02;A61K39/12;A61K39/145;A61K39/29;A61K39/39;A61K39/395;A61P31/04;A61P31/12;A61P31/16;A61P33/10;C12N7/00;(IPC1-7):A61K39/29;A61K45/00;A61K47/44 |
主分类号 |
A61K39/002 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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