| 摘要 |
<p>A method for treating a retroviral infection in a cell, tissue or animal so-infected by administering a retrovirus replication inhibitory amount of nitric oxide or a nitric oxide-delivering, releasing or transferring compound. A method for preventing or reversing retroviral latency in a cell, tissue or animal by administering thereto a nitric oxide synthase inhibitor in an amount sufficient to render retrovirus replication-competent. A method for the treatment of a latent retrovirus infection in a cell, tissue or animal by administering (i) a nitric oxide synthase inhibitor or nitric oxide scavenger in an amount sufficient to render the retrovirus replication-competent and (ii) a replication inhibitory amount of an antiviral agent. A composition comprising (i) a nitric oxide synthase inhibitor or nitric oxide scavenger in an amount sufficient to render the retrovirus replication-competent and (ii) a replication inhibitory amount of an antiviral agent in a pharmaceutically acceptable carrier.</p> |
