| 摘要 |
Proteins, including various dimeric and monomeric forms of the ob gene product, or modified ob protein-encoding DNA sequences, having anti-feeding activity and methods of preparing, purifying, formulating and using such proteins, for example, in the treatment of various feeding and metabolic disorders, including obesity and diabetes. Antibodies and immunoassays useful in the detection and quantitation of such proteins are also provided.
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| 申请人 |
AMYLIN PHARMACEUTICALS, INC.;BEELEY, NIGEL;RINK, TIMOTHY, J.;ALBRANDT, KEITH, ALAN;SIERZEGA, MICHAEL, EDWARD;JANES, SUSAN, M.;PRICKETT, KATHRYN, S.;PHELPS, JULIE, L.;CHUN, MARK;PARK, DOUGLAS, M.;BEIDLER, DANIEL, E. |
发明人 |
BEELEY, NIGEL;RINK, TIMOTHY, J.;ALBRANDT, KEITH, ALAN;SIERZEGA, MICHAEL, EDWARD;JANES, SUSAN, M.;PRICKETT, KATHRYN, S.;PHELPS, JULIE, L.;CHUN, MARK;PARK, DOUGLAS, M.;BEIDLER, DANIEL, E. |
