DERIVATIVES OF VITAMIN D, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD OF ITS PREPARING, TREATMENT METHOD

摘要

FIELD: vitamins. SUBSTANCE: invention relates to compounds of the formula (I) where X means hydrogen and hydroxy-group; Rand Rmean hydrogen or C-C-hydrocarbyl radical; or taken together with carbon atom supporting the group X they can form C-C-carbocyclic ring; Q means a single bond or C-C-hydrocarbylene biradical R,Rand/or Q can be optional substituted with one or more deuterium atoms or fluorine, and its derivatives. Synthesized compounds show antiinflammatory and immunomudulating action and high activity with regard to induction of differentiation and proliferation inhibition of some cells. EFFECT: improved method of synthesis, enhanced effectiveness of compounds.