摘要 |
FIELD: organic chemistry. SUBSTANCE: product: new compound of the formulawhere ring A and ring B, respectively, means at random substituted homo- or heterocyclic ring and at least one of their means at random substituted heterocyclic ring; ring means at random substituted benzene ring; R means hydrogen atom or at random substituted hydrocarbon residue; one of X and Y means -NRwhere Rmeans hydrogen atom or at random substituted hydrocarbon residue or -O-, and other means -CO- or -CS-, or one of their means -N= , and other means =CR- where Rmeans hydrogen atom, halogen atom, at random substituted hydrocarbon residue, at random substituted amino-group or at random substituted hydroxyl-group; n = 1 or 2, or its salts that show excellent antagonistic action to tachykinin receptors and inhibition effect on plasma transudation. EFFECT: improved method of synthesis, enhanced effectiveness. |