发明名称 HETEROCYCLIC COMPOUNDS, METHOD OF THEIR SYNTHESIS, PHARMCOMPOSITION AND METHOD OF TREATMENT
摘要 FIELD: organic chemistry. SUBSTANCE: product: new compound of the formulawhere ring A and ring B, respectively, means at random substituted homo- or heterocyclic ring and at least one of their means at random substituted heterocyclic ring; ring means at random substituted benzene ring; R means hydrogen atom or at random substituted hydrocarbon residue; one of X and Y means -NRwhere Rmeans hydrogen atom or at random substituted hydrocarbon residue or -O-, and other means -CO- or -CS-, or one of their means -N= , and other means =CR- where Rmeans hydrogen atom, halogen atom, at random substituted hydrocarbon residue, at random substituted amino-group or at random substituted hydroxyl-group; n = 1 or 2, or its salts that show excellent antagonistic action to tachykinin receptors and inhibition effect on plasma transudation. EFFECT: improved method of synthesis, enhanced effectiveness.
申请公布号 RU94040174(A) 申请公布日期 1996.10.10
申请号 RU19940040174 申请日期 1994.11.09
申请人 TAKEDA KEMIKAL INDASTRIZ;LTD. 发明人 KHIDEAKI NATSUGARI;TAKANORI ISKHIMA;TAKAJUKI DOI
分类号 C07D215/16;A61K31/44;A61K31/47;A61K31/4709;A61P23/00;A61P29/00;C07D401/04;C07D409/04;C07D471/04;C07D495/04;C07D513/04 主分类号 C07D215/16
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