| 发明名称 |
1-SUBSTITUTED VITAMIN D3 ANALOGUES |
| 摘要 |
Vitamine D3 analogues which include a hydroxyalkyl substituent in the 1-position and a modified D-ring side chain are described. These novel compounds are potent anti-proliferative substances with activity comparable to that of calcitriol but with a vitamin D3 receptor binding rating of approximately 10<-3> compared to that of calcitriol.
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| 申请公布号 |
WO9630338(A1) |
申请公布日期 |
1996.10.03 |
| 申请号 |
WO1996US03626 |
申请日期 |
1996.03.28 |
| 申请人 |
THE JOHNS-HOPKINS UNIVERSITY |
发明人 |
POSNER, GARY, H. |
| 分类号 |
C07C401/00;C07F9/53;(IPC1-7):C07C401/00;A61K31/59 |
主分类号 |
C07C401/00 |
| 代理机构 |
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| 主权项 |
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