METHODS FOR IDENTIFYING A FACTOR V GENE MUTATION

摘要

A method for identifying a Factor V gene mutation resulting in activated protein C resistance comprising detecting in a nucleic acid sample isolated from a human the presence of a genetic mutation characterized as a change from a guanine nucleotide to an adenine nucleotide at nucleotide postion 205 in exon 10 of the Factor V gene that is associated with replacement of arginine 506 by glutamine, thereby identifying said mutation.