METHOD FOR THE PREPARATION OF A N-ALKOXY-(TETRA- OR HEXAHYDRO)-PHTHALIMIDE AND METHOD FOR THE PREPARATION OF A N-ALKOXYAMINE

摘要

Method for the preparation of N-alkoxy-(tetra-or hexahydro)-phthalimide according to formula (I), R1 being methyl or ethyl and R2 and R3 being each independently of one another hydrogen or alkyl with 1-4C atoms of R2 and R3 together with the carbon atom to which they are bonded forming a ring with 5 or 6 C atoms, wherein the salt of the corresponding N-hydroxy-(tetrahydro- or hexahydro)-phthalimide according to formula II; with R2 and R3 as defined and M being an alkali metal, is brought into contact with R1Cl as alkylating agent, wherein R1 has the mentioned meaning. The N-alkoxy-(tetra- or hexahydro)-phthalimide can afterwards be converted with the aid of hydroxylamine sulphate into the corresponding alkoxyamine after which the alkoxyamine obtained can be isolated. In this manner a simple and commercially attractive process for the preparation of O-(m)ethylhydroxylamine can be implemented.