发明名称 PHARMACEUTICAL AGENTS CONTAINING METHOTREXATE DERIVATIVES
摘要 Compounds represented by general formula (I) or salts thereof, (wherein R1 represents a member selected from the group consisting of CH2, CH2CH2, CH2O, CH2S and CH2SO; R2 represents hydrogen, lower (C1-4) alkyl or benzyl; R3 represents COOR4, NHCOR5, CONR6R7, PO3H2 or SO3H; and n is an integer of from 1 to 4) which are useful as a remedy for autoimmune diseases such as systemic lupus erythematosus or nephritis such as glomerulonephritis.
申请公布号 CA2216647(A1) 申请公布日期 1996.10.03
申请号 CA19962216647 申请日期 1996.03.26
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人 MIHARA, MASAHIKO
分类号 A61K31/519;A61K31/5415;C07D475/08;(IPC1-7):A61K31/665;A61K31/505;A61K31/54 主分类号 A61K31/519
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