2-cyano-acrylic acid production

摘要

Prodn. of 2-cyanoacrylic acid (I) comprises the trans-esterification of a 2-cyanoacrylate (II) with an organic acid. Pref. the trans-esterification of (II), esp. the methyl, ethyl, n-propyl, isopropyl, n-butyl and/or isobutyl ester, is conveniently carried out using formic, acetic, propionic and/or butyric acid, esp. acetic acid, as the organic acid. It is conveniently carried out in the presence of a cation exchange resin as a catalyst, suitably at 10-130 deg C, esp. 40-90 deg C. The molar ratio of organic acid to (II) is typically 50:2, and 20-70 wt.% catalyst is advantageously used based on the total wt. of the reaction mixt..