发明名称 |
Formula and method for the prevention and treatment of hypercholesterolemia and cellular hyperproliferative disorders |
摘要 |
The present invention provides a formula and method for the prevention and treatment of hypercholesterolemia and cellular hyperproliferation. More specifically, the present invention provides a method for administering a formula including glucaric acid or a pharmaceutically acceptable salt thereof for the prevention and treatment of hypercholesterolemia and cellular hyperproliferation in humans and animals. It has been determined that glucaric acid and pharmaceutically acceptable salts thereof significantly lower the total and LDL level of serum cholesterol and inhibit cellular hyperproliferation when administered in therapeutic amounts. It is intended that glucaric acid or a pharmaceutically acceptable salt thereof is employed alone or in combination with other medicinal agents for the prevention and treatment of hypercholesterolemia and cellular hyperproliferation.
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申请公布号 |
US5561160(A) |
申请公布日期 |
1996.10.01 |
申请号 |
US19940317790 |
申请日期 |
1994.10.04 |
申请人 |
WALASZEK, ZBIGNIEW;SLAGA, THOMAS J.;HANAUEK, MARGARET |
发明人 |
WALASZEK, ZBIGNIEW;SLAGA, THOMAS J.;HANAUEK, MARGARET |
分类号 |
A61K31/045;A23L1/03;A23L1/30;A23L1/302;A23L1/304;A23L1/305;A61K31/07;A61K31/12;A61K31/19;A61K31/194;A61K31/215;A61K31/28;A61K31/30;A61K31/355;A61K31/375;A61K31/415;A61K31/42;A61K31/44;A61K31/455;A61K31/505;A61K31/51;A61K31/714;A61K33/00;A61K33/42;A61K45/06;A61P3/00;A61P3/06;A61P3/14;(IPC1-7):A61K31/19 |
主分类号 |
A61K31/045 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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