| 发明名称 |
Biosynthesis of rebeccamycin analogs by tryptophan analogs feeding |
| 摘要 |
<p>Addition of certain tryptophan analogs to the culture medium during fermentation of a rebeccamycin-producing strain of Saccharothrix aerocolonigenes results in production of new rebeccamycin analogs having advantageous antitumor properties.</p> |
| 申请公布号 |
GR3020163(T3) |
申请公布日期 |
1996.09.30 |
| 申请号 |
GR19960401487T |
申请日期 |
1996.06.06 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
LAM, KIN SING;SCHROEDER, DANIEL R.;MATTEI, JACQUELINE;FORENZA, SALVATORE;MATSON, JAMES A. |
| 分类号 |
C07H17/00;A61K31/70;A61K31/7042;A61K31/7052;A61P35/00;C07H19/044;C07H19/23;C12P19/28;C12P19/44;C12R1/01;C12R1/645;(IPC1-7):C07H19/04;A61K31/71 |
主分类号 |
C07H17/00 |
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