发明名称 |
Specific peptides for the treatment of deabetes mellitus |
摘要 |
The invention features peptides that are fragments of the human insulin C-peptide, which peptides include the sequence ELGGGPGAG or a fragment thereof, or the sequence EGSLQ or a fragment thereof. The peptides have the ability to stimulate Na+K+ATPase activity. Also provided are biomimetic organic compounds exhibiting activation of Na+K+ATPase activity and/or cellular binding to renal tubule cells and fibroblasts. Such peptides and compounds are useful in combating diabetes and diabetic complications, or for stimulating Na+K+ATPase activity. |
申请公布号 |
SE9603533(D0) |
申请公布日期 |
1996.09.27 |
申请号 |
SE19960003533 |
申请日期 |
1996.09.27 |
申请人 |
CREATIVE PEPTIDES SWEDEN AB |
发明人 |
JOHN WAHREN;BO-LENNART JOHANSSON;HANS JOERNVALL |
分类号 |
A61K38/00;A61K38/28;A61P3/10;C07K14/62;(IPC1-7):A61K/ |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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