发明名称 |
PAPILLOMA VIRUS-LIKE PARTICLES, FUSION PROTEINS ANPAPILLOMA VIRUS-LIKE PARTICLES, FUSION PROTEINS AND PROCESS FOR PRODUCING THE SAME D PROCESS FOR PRODUCING THE SAME |
摘要 |
In recombinant papilloma virus-like particles (VLP) derived from expression of viral structural proteins L1 and/or L2, the new feature is that at least one segment of these proteins is deleted but ability to form VLP is retained. Also new are: (1) fusion proteins (FP), esp. for prepn. of hybrid papilloma VLP (HVLP) consisting of a deleted L1 and/or L2 protein of a human papilloma virus (HPV) plus another protein (A) or its fragment; and (2) proteins (B), partic. for prepn. of HVLP, from which at least one L1/L2 segment has been deleted. |
申请公布号 |
WO9611272(A3) |
申请公布日期 |
1996.09.26 |
申请号 |
WO1995EP03974 |
申请日期 |
1995.10.09 |
申请人 |
MEDIGENE GESELLSCHAFT FUER MOLEKULARBIOLOGISCHE DIA;GISSMANN, LUTZ;ZHOU, JIAN;MUELLER, MARTIN;PAINSTIL, JEANETTE |
发明人 |
GISSMANN, LUTZ;ZHOU, JIAN;MUELLER, MARTIN;PAINSTIL, JEANETTE |
分类号 |
C12N15/09;A61K38/00;A61K39/12;A61P13/02;A61P15/00;A61P15/02;A61P31/12;C07K14/025;C07K19/00;C12N7/00;C12N7/04;C12N15/37;C12N15/62;C12P21/02;C12R1/19;C12R1/92 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|