| 摘要 |
A method for preparing alloactivated human donor lymphocytes for subsequent treatment of a tumor in a human patient, comprising the steps of: a) coculturing donor lymphocytes from a human donor ex vivo with leukocytes from the human patient so as to alloactivate the donor lymphocytes; and b) harvesting the alloactivated donor lymphocytes and preparing the alloactivated donor lymphocytes for human administration at a time after initiation of the coculturing when the alloactivated donor lymphocytes, upon implantation .in the bed of a solid tumor in the patient, are effective in the treatment of the tumor. This method is of use in treatment of glioblastoma in humans.
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