摘要 |
A method of inhibiting 5-lipoxygenase comprising administering to a mammal in need thereof an effective amount of a compound having formula (I), wherein R1 and R2 are independently hydrogen or C1-C6 alkyl; R3 is hydrogen, or a group of formula (a), wherein R4 is phenyl, substituted phenyl, naphthyl or substituted naphthyl, with the proviso that when R1 and R2 are both C1-C6 alkyl, R3 is not hydrogen; and pharmaceutically acceptable salts thereof.
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申请人 |
ELI LILLY AND COMPANY;CARLSON, DONALD, G.;CULLINAN, GEORGE, J.;FAHEY, KENNAN, J.;JACKSON, WILLIAM, T.;ROEHM, NEAL, W.;SPAETHE, STEPHEN, M. |
发明人 |
CARLSON, DONALD, G.;CULLINAN, GEORGE, J.;FAHEY, KENNAN, J.;JACKSON, WILLIAM, T.;ROEHM, NEAL, W.;SPAETHE, STEPHEN, M. |