| 摘要 |
<p>A method of inactivating pathogens present in blood products containing plasma protein and/or in whole blood intended for blood transfusion. In accordance with the teachings of the present invention, the method comprises treating the whole blood or blood product with formaldehyde in a concentration of about 0.05 %-0.25 %, preferably about 0.1 %-0.2 % and more preferably about 0.15 %, by weight of the whole blood or blood product so as to inactivate any pathogens present therewithin. The present invention is also directed to a method of treating a patient in need of whole blood or a blood constituent which comprises treating a sample of whole blood or a blood product comprising the blood constituent and plasma protein with formaldehyde in the manner described above and then administering the formaldehyde-treated blood or blood constituent to the patient in need thereof. Preferably, after the treating step and prior to the administering step, residual formaldehyde is removed from the blood sample.</p> |
