3,4-CYCLOAMIDRAZONES, PROCESS FOR PRODUCING THEM AND PHARMACEUTICALS CONTAINING THEM

摘要

The invention relates to partly novel 3,4-cycloamidrazones, a process for producing them and their use in pharmaceutical preparations. The 3,4-cycloamidrazones are lactam-aryl hydrazones and cycloimide-aryl hydrazones. They are produced by the reaction of activated lactam and cycloimide derivatives with aryl hydrazines or aryl hydrazine hydrochlorides. The 3,4-cycloamidrazones of the invention are highly effective lipoxygenase inhibitors and may be used in medicaments to treat all kinds of inflammations, allergic conditions, asthma, bronchitis and psoriasis.