发明名称 |
Transdermal drug delivery process |
摘要 |
<p>A calcitonin, its derivative or a salt thereof is transdermally delivered by iontophoresis in which a substantially constant voltage in the range of 3 to 20 V is applied at an electric current of 0.05 to 0.5 mA/cm<2>. In this process, the calcitonin can be delivered transdermally with a higher absorptivity by applying a higher voltage for a short period (at a voltage of about 6 to 14 V for about 5 to 15 minutes) in the initial stage of the voltage application, and then applying a lower voltage for a long period (at a voltage of about 3 to 9 V for about 30 to 40 minutes).</p> |
申请公布号 |
EP0732121(A1) |
申请公布日期 |
1996.09.18 |
申请号 |
EP19960104194 |
申请日期 |
1996.03.15 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD.;ADVANCE CO., LTD.;TEIKOKU HORMONE MFG. CO., LTD. |
发明人 |
IGA, KATSUMI;YANAI, SHIGEO;OKABE, KEIICHIRO;ITOH, MASAKI |
分类号 |
A61N1/30;A61N1/32;(IPC1-7):A61N1/30 |
主分类号 |
A61N1/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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