发明名称 |
Quinazolinone derivatives possessing calcium uptake inhibiting activity |
摘要 |
This invention is to provide quinazolinone derivatives, and their acid salts and quaternary ammonium salts, having an effect of preventing or treating diseases caused by calcium ion overload in cells, such as ischemic heart disease, ischemic cerebral disease and ischemic renal disease, and their usage. The quinazolinone derivatives are represented by the formula: <IMAGE> (1) typically, T represents an oxygen atom; Y represents a phenyl or cyclohexyl group; R1 represents a hydrogen or chlorine atom; R2 represents a hydrogen atom; ring W represents a benzene or pyridine ring; Z represents a group of the formula: <IMAGE>
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申请公布号 |
US5556860(A) |
申请公布日期 |
1996.09.17 |
申请号 |
US19940249212 |
申请日期 |
1994.05.26 |
申请人 |
SUMITOMO PHARMACEUTICALS CO., LTD. |
发明人 |
MURAOKA, MASAMI;MATSUI, KAZUKI;HASEGAWA, HIROHIKO;KOJIMA, ATSUYUKI |
分类号 |
A61K31/505;A61K31/535;C07D239/82;C07D401/04;C07D401/06;C07D401/14;C07D403/04;C07D403/06;C07D405/14;C07D409/14;C07D413/06;C07D453/02;C07D471/04;C07D495/04;(IPC1-7):C07D239/82;C07D239/84;A61K31/435 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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