Polyazamacrocycle chelating agents with amide linkages

摘要

PCT No. PCT/EP91/02118 Sec. 371 Date Feb. 22, 1994 Sec. 102(e) Date Feb. 22, 1994 PCT Filed Nov. 6, 1991 PCT Pub. No. WO92/08707 PCT Pub. Date May 29, 1992Macrocyclic chelating agents, optionally possessing more than one macrocyclic ring having at least two peptide linkages within the macrocyclic skeleton. The chelating agents are used for the preparation of paramagnetic metal chelates for use as MRI contrast agents.