发明名称 |
Interleukin-2/viral antigen protein chimers |
摘要 |
Disclosed are (1) a fused protein obtained by combining an antigen used for vaccine and a lymphokine by the application of gene engineering, (2) a recombinant DNA containing a nucleotide sequence coding for the above fused protein, (3) a transformant bearing the above recombinant DNA, (4) a method for producing the fused protein which comprises cultivating the above transformant, producing and accumulating the above fused protein in a culture, and collecting the fused protein, and (5) a hybrid protein obtained by chemically combining an antigen used for vaccine with a lymphokine. The resulting fused and hybrid proteins have strong immunogenicity.
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申请公布号 |
US5556946(A) |
申请公布日期 |
1996.09.17 |
申请号 |
US19950386354 |
申请日期 |
1995.02.08 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
FUJISAWA, YUKIO;HINUMA, SHUJI;AONO, AKI |
分类号 |
A61K39/00;C07K14/035;C07K14/04;C07K14/16;C07K14/55;C07K16/08;C12N1/21;C12N15/26;C12N15/38;C12N15/48;(IPC1-7):A61K38/20;C12N15/62 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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