发明名称 IONIC 5-C-SUBSTITUTED 2,4,6-TRIIODO-ISOPHTHALIC ACID DERIVATIVES AND THEIR MANUFACTURE AND USE
摘要 Ionic compounds of the formula <IMAGE> wherein X is -CONR1R2, -CH2NHxAcyl or -CH2OH; Y is -NR3R4, -NHxAcyl or OR5; R1, R2, R3 and R4 can be identical or different, and each is hydrogen, C1-6- alkyl or C2-8-alkyl substituted by 1-5 OH groups and/or by one C1-3-alkoxy group, R5 is C1-6 alkyl or C2-8-alkyl substituted by 1-5 OH groups and/or by one C1-3-alkoxy group, and Acyl, which can be the same or different in X and Y, is C2-6-alkanoyl or C2-6-alkanoyl substituted by 1-4 OH groups and/or by one C1-3-alkoxy group, or a physiologically compatible salt thereof with an inorganic or organic base, have valuable properties as X-ray contrast agents.
申请公布号 ZA8100148(B) 申请公布日期 1982.01.27
申请号 ZA19810000148 申请日期 1981.01.09
申请人 SCHERING AG 发明人 MUETZEL WOLFGANG;GRIES HEINZ;PFEIFFER HEINRICH;SPECK ULRICH
分类号 C07C69/80;A61K31/16;A61K31/165;A61K31/19;A61K31/235;A61K31/24;A61K49/04;C07C;C07C55/00;C07C61/00;C07C63/08;C07C63/10;C07C63/30;C07C63/307;C07C63/68;C07C67/00;C07C69/76;C07C231/00;C07C233/47;C07C233/65;C07C233/69;C07C233/92;C07C235/42;C07C237/30;C07C237/46;C07F13/00 主分类号 C07C69/80
代理机构 代理人
主权项
地址