ANTIGEN PRESENTING SYSTEM AND METHODS FOR ACTIVATION OF T-CELLS
摘要
The present invention relates to synthetic antigen-presenting matrices, their methods of making and their methods of use. One such matrix is cells that have been transfected to produce MHC antigen-presenting molecules and assisting molecules such as co-stimulatory molecules. The matrices can be used to activate CD8+ T-cells to produce cytokines and become cytotoxic.
申请公布号
CA2214649(A1)
申请公布日期
1996.09.12
申请号
CA19962214649
申请日期
1996.03.08
申请人
THE SCRIPPS RESEARCH INSTITUTE
发明人
CAI, ZELING;LUXEMBOURG, ALAIN M. D.;MORIARTY, ANN M.;BRUNMARK, ANDERS;PETTERSON, PER A.;JACKSON, MICHAEL;SPRENT, JONATHAN;LETURCQ, DIDIER JEAN