| 发明名称 |
1-aryl-2-acylamino-ethane compounds and their use as neurokinin especially neurokinin 1 antagonists |
| 摘要 |
PCT No. PCT/EP96/00555 Sec. 371 Date Aug. 21, 1997 Sec. 102(e) Date Aug. 21, 1997 PCT Filed Feb. 9, 1996 PCT Pub. No. WO96/26183 PCT Pub. Date Aug. 29, 19961-Aryl-2-acylaminoethane compounds of formula I wherein R1-R4, X and Am are as defined in the description, have valuable pharmaceutical properties and are especially effective as NK-1 antagonists. |
| 申请公布号 |
AU4623396(A) |
申请公布日期 |
1996.09.11 |
| 申请号 |
AU19960046233 |
申请日期 |
1996.02.09 |
| 申请人 |
CIBA-GEIGY AG |
发明人 |
DR. MARC GERSPACHER;ANDREAS VON SPRECHER;SILVIO ROGGO;ROBERT MAH;DR. SILVIO OFNER;SIEM JACOB VEENSTRA;CLAUDIA BETSCHART;YVES AUBERSON;WALTER SCHILLING |
| 分类号 |
C07D249/08;A61K31/16;A61K31/165;A61K31/40;A61K31/4015;A61K31/403;A61K31/404;A61K31/405;A61K31/41;A61K31/415;A61K31/4184;A61K31/425;A61K31/44;A61K31/4427;A61K31/443;A61K31/445;A61K31/4468;A61K31/451;A61K31/454;A61K31/47;A61K31/495;A61K31/496;A61K31/505;A61K31/535;A61K31/5355;A61K31/5375;A61K31/55;A61P1/00;A61P9/00;A61P11/00;A61P11/06;A61P25/00;A61P29/00;A61P37/08;A61P43/00;C07C231/02;C07C231/12;C07C237/22;C07C255/29;C07C311/51;C07D207/27;C07D209/08;C07D209/12;C07D209/18;C07D209/20;C07D211/16;C07D211/22;C07D211/44;C07D211/48;C07D211/58;C07D211/62;C07D213/40;C07D213/70;C07D213/81;C07D215/46;C07D223/12;C07D223/16;C07D231/38;C07D233/60;C07D235/16;C07D235/28;C07D239/28;C07D239/42;C07D241/14;C07D241/20;C07D295/13;C07D295/135;C07D295/14;C07D295/18;C07D295/185;C07D401/12;C07D403/12;C07D405/12;C07D417/12;C07D471/10;C07D521/00 |
主分类号 |
C07D249/08 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
