发明名称 |
Polypeptides useful as immunotherapeutic agents and methods of polypeptide preparation |
摘要 |
Fusion polypeptides and aggregates of polypeptides comprising papillomavirus-derived antigens, and compositions thereof and their use e.g. with adjuvants for immunogenic and vaccine purposes in eliciting e.g. HPV-specific immune responses. The polypeptides can be purified to result in aggregates which when in solution or dispersion can pass through a sterilisation filter, and in amorphous aggregates. An example of such a polypeptide is a fusion protein of human papillomavirus proteins L2 and E7. |
申请公布号 |
AU4727296(A) |
申请公布日期 |
1996.09.11 |
申请号 |
AU19960047272 |
申请日期 |
1996.02.23 |
申请人 |
CANTAB PHARMACEUTICALS RESEARCH LIMITED |
发明人 |
NIGEL RICHARD WHITTLE;JEREMY PADDON CARMICHAEL;STEPHEN EDWARD CONNOR;HENRY STEPHEN GRAMMER THOMPSON;MARK JONATHAN WILSON |
分类号 |
C12N15/09;A61K39/12;A61P31/12;C07K14/025;C07K19/00;C12N15/00;C12N15/37;C12P21/02;C12R1/92 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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