| 摘要 |
PROBLEM TO BE SOLVED: To obtain a preparation containing a specific benzofuran derivative, effective for bone loss of female after climacteric, patients whose wombs are extracted, patients of long-term administration of corticosteroid, patients of Cushing syndrome and patients of growth abnormality of sexual organs, etc. SOLUTION: This preparation contains a compound of the formula (R is H or methyl; R<1> and R<2> are each methyl, ethyl or a saturated heterocyclic group forming group together with N bonded them; X is Br, Cl, F or H) (salt) e.g. 2-(p-chlorobenzyl)-3-[p-(2-dimethylaminoethoxy)phenyl]-6-methoxy- benzo[b]furan}. The dose of the compound of generally about 0.1-1,000 mg/day (especially about 50-600 mg/day) and administered about once to about three times dividedly daily. The preparation has negligible adverse effects or has no adverse effects at all. |
