| 发明名称 |
2'-DEOXY-2'-METHYLIDENECYTIDINE DIHYDRATE, METHODS FOR ITS PRODUCTION AND COMPOSITIONS |
| 摘要 |
Disclosed are novel 2'-deoxy-2'-methylidenecytidine (DMDC) dihydrate, its methods for production, and compositions with improved solubility containing same. The dihydrate is more stable and less hygroscopic than its corresponding acid addition salt, such as hydrochloride,and is useful as an antitumor or antiviral agent. Also disclosed is a composition of DMDC dihydrate further stabilized by a saccharide.
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| 申请公布号 |
CA2036507(C) |
申请公布日期 |
1996.09.10 |
| 申请号 |
CA19912036507 |
申请日期 |
1991.02.18 |
| 申请人 |
YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD.;YAMASA SHOYU CO., LTD. |
发明人 |
SAKATA, SHINJI;MIYASHITA, TAKANORI;KONDO, KAZUHIKO;SAKAI, ATSUSHI;SHIBATA, TOSHIYUKI;OGAWA, TAKAYUKI |
| 分类号 |
A61K9/00;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7064;A61K31/7068;A61K47/12;A61K47/26;A61P31/12;A61P35/00;C07H19/06;(IPC1-7):C07H19/073 |
主分类号 |
A61K9/00 |
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