发明名称 APPLICATION OF METHYLMETHIONINESULFONIUM DIAQUATRICHLOROCUPRATE AS A STIMULATOR OF LIVER BIOSYNTHETIC FUNCTION
摘要 FIELD: chemical-pharmaceutical industry. SUBSTANCE: invention relates to application of the early known methylmethioninesulfonium diaquatrichlorocuprate of the formula (I). Compound shows positive effect on liver and decreases activity of aspartic acid aminotransferase and alkaline phosphatase and total bilirubin content in animal damaged liver (by 12.12; 32.24 and 52.62%, respectively) and increases total protein level in blood serum by 8.15%. Agent improves result of colloidal-precipitating reaction. Agent can be used as medicinal drug for recovery of morphofunctional liver state, its protein-synthetic and detoxicating functions. Agent shows low toxicity, its LD= 850 mg/kg at intraperitoneal administration to white mice. EFFECT: low toxicity, broad spectrum of therapeutic action, hepatotropic action.
申请公布号 RU94011850(A) 申请公布日期 1996.09.10
申请号 RU19940011850 申请日期 1994.04.05
申请人 BAJMATOV V.N. 发明人 BAJMATOV V.N.;GAJFUTDINOVA R.K.;IVANOVA T.A.;PRIKAZCHIKOV O.M.;ALVERDIEV G.R.
分类号 A61K31/195 主分类号 A61K31/195
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