| 摘要 |
(Hetero)aryl substd. aminoalkanoic acid amides and alkanoic acid diamides (I) and their salts are new: R<1> = 2-Ra-3-Rb-phenyl; 2-Ra-4-Rc-phenyl; 2-Ra-pyridin-3-yl; 3-Ra-pyridin-2-yl; or 1-Rd-indol-3-yl; one of Ra and Rb = aliphatic or hetero cycloaliphatic-aliphatic gp. or OH opt. etherified by aliphatic, araliphatic or heteroaraliphatic gp.; and the other = H, aliphatic gp. or opt. esterified or amidated COOH; Rc = H, aliphatic gp., OH opt. etherified by aliphatic, araliphatic, heteroarylaliphatic or heterocycloaliphatic-aliphatic gp.; or NH2 (opt. heteroaliphatically substd.); Rd = aliphatic, araliphatic or heteroaliphatic gp.; one of X1 and X2 = CO and the other = CH2; R2 = aliphatic gp.; R3 = NH2 (opt. aliphatically substd.); R4 = aliphatic or araliphatic gp.; R5 = aliphatic or cycloaliphatic-aliphatic gp.; opt. hydrogenated and/or oxo-substd. heteroaryl; or lower alkyl substd. by C-bonded opt. hydrogenated and/or oxo-substd. heteroaryl or heteroaliphatic gp.. |
