| 摘要 |
PCT No. PCT/FI91/00413 Sec. 371 Date Jun. 30, 1993 Sec. 102(e) Date Jun. 30, 1993 PCT Filed Dec. 30, 1991 PCT Pub. No. WO92/12426 PCT Pub. Date Jul. 23, 1992A rapid diagnostic method for detecting the rupture of fetal membranes is disclosed. The presence of insulin-like growth factor binding protein 1 (IGFBP-1) in a vaginal secretion sample, resulting from the rupture of fetal membranes, is detected with the aid of at least one specific binding substance for IGFBP-1 .
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