发明名称 |
2-BENZYL-3-ARYLBENZOTHIOPHENES |
摘要 |
<p>The present invention provides derivatives of 2-phenylmethyl-3-[4-(2-aminoethoxy)phenyl]-benzo[b]thiophene. The present invention further provides pharmaceutical compositions containing these derivatives and the use of such compounds alone, or in combination with estrogen or progestin, for alleviating the symptoms of post-menopausal syndrome, particularly osteoporosis, cardiovascular related pathological conditions, and estrogen-dependent cancer. These compounds are also useful for inhibiting uterine fibroid disease and endometriosis in women and aortal smooth muscle cell proliferation, particularly restenosis, in humans.</p> |
申请公布号 |
WO9626935(A1) |
申请公布日期 |
1996.09.06 |
申请号 |
WO1996US02585 |
申请日期 |
1996.02.27 |
申请人 |
ELI LILLY AND COMPANY;CULLINAN, GEORGE, J.;SALES, JAMES, J. |
发明人 |
CULLINAN, GEORGE, J.;SALES, JAMES, J. |
分类号 |
A61K31/38;A61K31/381;A61K31/40;A61K31/445;A61K31/535;A61P3/02;A61P3/06;A61P9/00;A61P13/02;A61P15/00;A61P43/00;C07D333/56;(IPC1-7):C07D333/64;C07D333/72;C07D409/12;C07D413/12 |
主分类号 |
A61K31/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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