| 摘要 |
<p>New compositions of matter and methods of employing the novel compositions to deliver gene(s) to cells is provided. The compositions of the invention, which comprise a liposomal preparation(s), a nucleic acid molecule(s) and a perpetuation molecule(s) promote the efficient introduction and stable expression of chimeric genes present in the nucleic acid molecule within cells by providing specific mechanisms supporting entry, trafficking, and integration of those molecules within cells. Particular advantages of the invention include greater efficiency and safety than viral methods, combined with stable expression previously obtainable only from viral delivery systems.</p> |
