The present invention concerns a method for detecting the presence of a catalytically active ribozyme in a medium. The detection of the catalytically active ribozyme may be a goal by itself, or the ribozyme may serve as a reporter for the presence of other biomolecules in an assayed sample. The detection is carried out in a catalytic system wherein the presence of the active ribozyme serves to produce other active ribozyme in a positive-feedback amplificatory manner.
申请公布号
WO9627026(A1)
申请公布日期
1996.09.06
申请号
WO1996US02380
申请日期
1996.02.27
申请人
INTELLIGENE LTD.;ASHER, NATHAN;TIKOCHINSKI, YARON;KRUPP, GUIDO;GRINBERG, JACOB;FRIEDMANN, ADAM
发明人
ASHER, NATHAN;TIKOCHINSKI, YARON;KRUPP, GUIDO;GRINBERG, JACOB;FRIEDMANN, ADAM