| 摘要 |
PCT No. PCT/EP96/00835 Sec. 371 Date Aug. 25, 1997 Sec. 102(e) Date Aug. 25, 1997 PCT Filed Mar. 1, 1996 PCT Pub. No. WO96/27022 PCT Pub. Date Sep. 6, 1996In accordance with a novel process, (R)-amines of the formula <IMAGE> (I) in which R1, R2 and n have the meanings given in the description, can be prepared by reacting reating N-acyl-amines of the formula <IMAGE> (II) in which R1, R2, R3 and n have the meanings given in the description, with lipases which are suitable for cleaving the (R)-enantiomers of N-acyl-amines of the formula (II), in the presence of water and optionally in the presence of an organic diluent, at a pH of between 3.0 and 10.0 and at temperatures of between 0 DEG C. and 80 DEG C. |
