Bioreactor

摘要

A bioreactor operable even for substrates difficult to attain sufficient dispersion, such as insoluble solid substrate liable to float up or to sediment down in the reactor vessel and highly viscous or highly concentrated substrates, by realizing uniform dispersion and mixing of the substrate in the reaction mixture and an excretion of the reaction product with sieving, permitting thus a continuous operation of the reactor under a reliable maintenance of invariability of the reaction condition for a long period of time, which bioreactor comprises A reaction vessel 1 having a reaction chamber 2 surrounded by a water jacket 3 for maintaining a predetermined constant temperature, the reaction chamber 2 being provided in the vicinity of the inner wall surface 2a of the reaction vessel 2 with a plurality of upright screws 6 and 7 in an adjoining relationship to each other each having a screw thread or a helical fin 6b, 7b of reverse turning sense with each other, wherein the reactor vessel contents are subjected to a convectional flow induced by the rotation of the screws in the reverse sense to each other by a gearing 14, 15, whereby the substrate therein is subjected to a uniform agitation and to a milling and sieving actions in the portion 13 where the fins of the screws are facing to each other, before the reaction product is excreted by a screw conveyer 25.